NADH 60 capsules – NOW

NADH 10 mg and 200 mg ribose, NOW, 60 vegetarian capsules

NADH 10 mg + 200 mg Ribose combines stabilized NADH with D-ribose.

NADH is a form of niacin-related coenzyme that occurs naturally in the body’s cells and is involved in processes related to energy metabolism. D-ribose is a simple sugar that the body uses to produce ATP.

NADH is a molecule that the body already produces naturally and that plays a central role in the conversion of food into cellular energy. NADH is an abbreviation for nicotinamide adenine dinucleotide (the letter “H” stands for hydrogen, indicating that it transports electrons) and acts as an electron carrier inside cells, where it supplies the chemical fuel that mitochondria need to produce ATP, the body’s primary energy currency. Most people who look for NADH supplements are interested in boosting their energy levels, improving their cognitive function, or managing chronic fatigue.

We also carry NAD+ from Helhetshälsa

How NADH Works in the Body—We’ll Take a Closer Look (Get a Little Technical) at NADH and NAD+

NADH and its partner molecule, NAD+, form a two-part system that supplies energy to nearly all the cells in the body. When you eat, your body breaks down carbohydrates, fats, and proteins through a series of chemical reactions (glycolysis, the TCA cycle, and fat oxidation). During these reactions, NAD+ accepts electrons and is converted to NADH. NADH is then transported to the mitochondria, where it transfers the electrons via the so-called electron transport chain. This process, oxidative phosphorylation, is how your cells generate the vast majority of their ATP.

You can think of NAD+ as an empty truck and NADH as the loaded version. The constant alternation between these two forms is what keeps energy production going. In addition to providing energy, NAD+ also serves as a building block for enzymes involved in DNA repair and cell maintenance, including sirtuins and PARPs—proteins linked to aging and stress responses. NAD+ levels decline with age, which has led “biohackers” to take an interest in NADH.

NADH Supplements vs. NAD+ Precursors

This is where it gets a little confusing. NADH supplements directly supply the reduced (electron-laden) form of the molecule. Other popular supplements, such as NR (nicotinamide riboside) and NMN (nicotinamide mononucleotide), take a different approach: they provide the building blocks that the body uses to produce NAD+. These are fundamentally different strategies. NADH provides you with the form that is ready to donate electrons for energy production. NAD+ precursors provide the body with the building blocks to create a larger total NAD pool, which then switches between the two forms as needed.

NADH supplements have been studied since the 1990s, while NR and NMN are more recent supplements. If your primary interest is cellular energy production, NADH is the more direct route. If you focus on the broader anti-aging and DNA repair functions associated with NAD+ levels, precursors such as NR or NMN may be more relevant.

Energy and Chronic Fatigue

The most common reason people take NADH is fatigue, and the most studied area is chronic fatigue syndrome. In clinical trials, oral NADH has been tested at doses of 5 mg twice daily or 10 mg once daily for 8 to 12 weeks, sometimes in combination with CoQ10. The reasoning is simple: if mitochondrial energy production is impaired in CFS patients, providing more of this electron carrier should help.

The results have been mixed. Some smaller studies have reported improvements on the fatigue scale, but these studies tend to be small and short-term. A large registered study (CONNeCT) tested a combination of CoQ10 and NADH at a dose of 20 mg per day for 8 weeks in patients with CFS/ME, but the results have not been widely published in a way that confirms clear benefits. When it comes to general fatigue in otherwise healthy individuals, there is little clinical evidence that NADH supplementation has any noticeable effect.

Cognitive Function and Brain Health

NADH has an interesting relationship with the brain’s chemistry and function. In laboratory studies, NADH increased dopamine production in nerve cells by accelerating the recycling of a cofactor (tetrahydrobiopterin) that the dopamine-producing enzyme needs to function. More efficient reuptake of the cofactor leads to increased dopamine production. This mechanism has sparked interest in the use of NADH in neurodegenerative conditions characterized by dopamine depletion, particularly Parkinson’s disease.

In a randomized, double-blind study of Alzheimer’s disease, 26 patients received either 10 mg of NADH daily or a placebo for six months. The NADH group showed no progressive cognitive decline during that period and scored significantly higher on a standardized dementia scale compared with the placebo group. The differences were most pronounced in terms of verbal fluency and visual-constructive ability.

Athletic Achievements

If you’re considering taking NADH to improve your workouts or your physical endurance, the research findings are unclear or uncertain. A controlled study testing four weeks of NADH supplementation showed no improvements in VO2 max, maximum anaerobic running time, blood lactate levels, reaction time, or subjective fatigue compared with placebo. The only bright spot was a small but statistically significant improvement in explosive leg strength. However, this single finding is not sufficient to recommend NADH as a general dietary supplement for athletes.

NADH in the diet and natural (endogenous) production

The body continuously produces its own NADH from building blocks obtained from the diet. The daily requirement for maintaining NAD levels can be met with about 15 mg of niacin (vitamin B3) per day, which is found in abundance in meat, fish, and dairy products. The body can also synthesize NAD from the amino acid tryptophan, which is found in chicken, eggs, and cheese.

Other NAD precursors are found in smaller amounts in plant-based foods. Broccoli contains 0.25 to 1.88 mg of NMN per 100 grams, while avocados and tomatoes provide 0.26 to 1.60 mg per 100 grams.

Interestingly, calorie restriction has been shown to increase NAD+ levels while lowering NADH levels, which activates sirtuins in the process. It is one of the proposed mechanisms underlying the potential benefits of calorie restriction.

Who can benefit most from NADH supplements?

The strongest—albeit still limited—evidence for NADH supplementation pertains to people with chronic fatigue syndrome and those in the early stages of cognitive decline. For these groups, 10 mg daily for at least 8 weeks is the most commonly tested dosing regimen. Healthy adults seeking a general energy boost or a performance advantage in sports will (according to current research) likely not notice any significant effects. The supplement’s role in dopamine production is biologically interesting, but it remains unclear how effective it is.

NADH occupies an unusual place in the world of dietary supplements: the underlying biology is well established and truly important, but the evidence that taking it in capsule form clearly alters mitochondrial function remains inconclusive. Despite this, many users report noticing improvements in their energy levels, and there are groups for whom trying NADH is of the greatest interest: those with chronic fatigue syndrome and those in the early stages of cognitive decline.

Nutritional Value per Daily Dose (1 capsule):
NADH (PANMOL®-NADH) 10 mg
D-ribose (Bioenergy RIBOSE®) 200 mg

Ingredients: NADH (PANMOL®-NADH) (reduced β-nicotinamide adenine dinucleotide), D-ribose (Bioenergy RIBOSE®), hypromellose (cellulose capsule), microcrystalline cellulose, stearic acid (vegetable source), magnesium stearate (vegetable source), silicon dioxide, and beeswax.